- 1 USE
29A Go through
47356 - 2 ICE
46A Main ingredient of the Puerto Rican dessert piragua
40391 - 3 STAR
48D Have the lead
31316 - 4 UNO
53D ___ Show 'Em No Mercy (card game variant)
30241 - 5 TIL
37A "It was news to me," in online shorthand
29169 - 6 LOT
51D Fate
25189 - 7 ARENA
36A Play place
24334 - 8 STP
9D Indy label
23172 - 9 ATT
19A Quarterback's stat: Abbr.
23161 - 10 TEL
49A It's a no.
17183 - 11 UPS
4D High times
17123 - 12 LEA
22A Broadway's Salonga
14261 - 13 CHE
33D "Guerrillero Heroico" subject, familiarly
14162 - 14 YODA
45A Iconic role for Frank Oz
1273 - 15 SEN
32D Kamala Harris, once: Abbr.
11184 - 16 SECT
5D Sunni or Shia, e.g.
11137 - 17 DENS
26A Where the lions sleep tonight, presumably
11125 - 18 BAIL
8D Flake
1150 - 19 ADMIT
38A Take in
973 - 20 ORATOR
2D Podium figure
853 - 21 ARNIE
7D Nickname for an early 2000s governor of California
793 - 22 SOPS
42A Concessions
747 - 23 LOIS
23A Lowry who wrote "The Giver"
676 - 24 TITO
47D "La Clemenza di ___" (Mozart opera)
598 - 25 PANSY
43D Violet variety
532 - 26 SOLVE
25A Work out
526 - 27 MANIA
28D Fever pitch
464 - 28 IDIOTS
54A Yo-yos
423 - 29 PEELS
43A Some compost bin detritus
422 - 30 ABSORB
7A Suck up
419 - 31 IREPEAT
13A "This cannot be stressed enough …"
419 - 32 ASITIS
36D "Currently …"
415 - 33 PLAZA
30D Square
333 - 34 PRATT
30A One of the "Hollywood Chrises"
324 - 35 SNARK
44D Tone of many tweets
322 - 36 ROBUST
1A Hearty
316 - 37 BESTIE
3D Closest confidant, informally
310 - 38 BROCODE
35D Male protocol popularized by "How I Met Your Mother"
35 - 39 IDEATE
40D Conceptualize
247 - 40 BREAST
12D See 18-Across
210 - 41 OHPLEASE
10D "Come on, that's just ridiculous"
26 - 42 BRAINFREEZE
35A Head cold?
25 - 43 DREAM
27A Concoct, with "up"
142 - 44 TALUS
6D Bone connected to the fibula
113 - 45 GRANITE
55A Mount Rushmore's makeup
112 - 46 RATHER
15A Fairly
112 - 47 RIBALD
1D Bawdy
110 - 48 RELENTS
11D Lets up
19 - 49 MOTRIN
39D Tylenol alternative
18 - 50 KRONER
57A Scandinavian capital
17 - 51 SAMOANS
24D Ethnic minority in New Zealand
17 - 52 TALLER
41D Like firstborn children vis-à-vis second-born children, statistically
17 - 53 NIPPLE
18A Occasionally censored part of the 12-Down
15 - 54 TOMLIN
50A Fonda's co-star on "Grace and Frankie"
15 - 55 TUNAOIL
20A Canned liquid rich in essential fatty acids
14 - 56 DRAMEDY
26D It'll make you laugh, it'll make you cry
13 - 57 SEXTOY
56A What might be included in an act of congress
13 - 58 BASSCLEF
16A Cello parts are written in it
12 - 59 DNATURAL
52A Another name for C##
12 - 60 TANNINS
47A Compounds in tea and wine
12 - 61 11
- 62 11
- 63 11
- 64 11
- 65 11
- 66 11