Ordered by uses in the last three years (since 2023-11-02), then by uses across the whole archive.

1. AnswerLast 3 yearsAll time
2. 1
   ASEA

   46D Between ports

   22
   326
3. 2
   TRIO

   48D The Magi, e.g.

   21
   204
4. 3
   RARE

   22A Like tritium and triplets

   19
   257
5. 4
   ORSO

   44A "Ish"

   17
   145
6. 5
   SOAR

   42A Take off

   15
   125
7. 6
   ALIEN

   38A Unearthly

   13
   179
8. 7
   PEST

   40A Annoyance

   13
   128
9. 8
   ROSA

   8D Gift on el 14 de febrero

   11
   137
10. 9
    YENS

    23A Thirsts

    11
    123
11. 10
    LIEN

    27D Home security measure

    9
    131
12. 11
    BEAU

    43A Sender of a billet-doux

    9
    74
13. 12
    PTAS

    5D Ed promoters

    8
    87
14. 13
    SITS

    6D Goes unused

    7
    68
15. 14
    FENCE

    7D Cross swords

    6
    33
16. 15
    NACL

    47D It reacts with H2SO4

    5
    47
17. 16
    GYRO

    25D Street cart offering

    5
    34
18. 17
    PECK

    28D Hit with the bill?

    5
    33
19. 18
    PEONS

    39D Drones

    4
    37
20. 19
    ASCEND

    38D Move up the ranks

    4
    19
21. 20
    ESSENCE

    37D Pith

    3
    43
22. 21
    TOSSED

    41D Got rid of

    3
    17
23. 22
    INSECTS

    17A Web feed?

    3
    14
24. 23
    ITERATE

    16A Say, say, say?

    2
    35
25. 24
    BAKE

    21A Excessively tan

    2
    34
26. 25
    YESYES

    12D "All right already!"

    2
    28
27. 26
    MRIS

    20A Some hosp. tests

    2
    26
28. 27
    SCIENCE

    52A "The great antidote to the poison of enthusiasm and superstition," per Adam Smith

    2
    23
29. 28
    TEABAGS

    14D Things steeped in tradition?

    2
    13
30. 29
    ZITS

    24D Dreaded dermal development

    2
    12
31. 30
    EASESIN

    49A Gets one's feet wet

    2
    11
32. 31
    CATERER

    2D One serving a function

    2
    10
33. 32
    DENTAL

    53A With 39-Across, teeth-cleaning aid

    2
    10
34. 33
    PERCENT

    33D Kind of yield

    2
    8
35. 34
    ALOHAOE

    31D Song sung to Lilo in "Lilo & Stitch"

    1
    15
36. 35
    PICK

    39A See 53-Across

    1
    15
37. 36
    PYREX

    28A Flask material

    1
    11
38. 37
    FRIDAY

    7A Man ___

    1
    10
39. 38
    SCAMPS

    1A Little rascals

    1
    8
40. 39
    LICKS

    15D Affection from a pooch

    1
    6
41. 40
    VACUUMS

    30D Suckers

    1
    3
42. 41
    INERROR

    9D Mistakenly

    0
    24
43. 42
    ALPES

    31A Mont Cervin and others

    0
    14
44. 43
    LEONINE

    15A Like some roars

    0
    14
45. 44
    ADELINE

    3D Virginia Woolf's given name at birth

    0
    13
46. 45
    ZAGS

    24A Suddenly changes direction

    0
    13
47. 46
    LACOSTE

    34A Tennis star nicknamed Le Crocodile

    0
    8
48. 47
    LIAISON

    32D Intermediary

    0
    8
49. 48
    SPOILED

    35D Like a rained-on parade

    0
    7
50. 49
    ITSOVER

    29A Gist of a Dear John letter

    0
    6
51. 50
    BGIRL

    43D Female hip-hop fan

    0
    5
52. 51
    HADATIT

    13A Joined the fray

    0
    5
53. 52
    ANTHRAX

    11D One of the "Big Four" thrash metal bands

    0
    4
54. 53
    DICTATE

    10D State for the record

    0
    4
55. 54
    LODGED

    54A Registered, as a complaint

    0
    3
56. 55
    NOONERS

    51A Certain trysts

    0
    3
57. 56
    REALIGN

    26A Change affiliations

    0
    3
58. 57
    SHIMMY

    1D Shake on the dance floor

    0
    2
59. 58
    CHICAGOSUNTIMES debut

    45A Where Roger Ebert's reviews appeared for 47 years

    0
    1
60. 59
    GOTAS debut

    25A Received high marks

    0
    1
61. 60
    MAGNOLIAS debut

    19D Pair on Mississippi's state quarter

    0
    1
62. 61
    MARISSA debut

    4D ___ Mayer, Yahoo C.E.O. beginning in 2012

    0
    1
63. 62
    MARLINS debut

    50A Team "spawned" in 1993

    0
    1
64. 63
    MELISSAMCCARTHY debut

    18A Player of Molly on "Mike & Molly"

    0
    1
65. 64
    TERMING debut

    36D Giving a name

    0
    1