| 2026-02-08 | What Excedrin relieves |
| 2024-12-31 | Cause of a grimace |
| 2024-08-18 | Total headache |
| 2024-01-25 | Total hassle |
| 2023-09-17 | Major inconvenience |
| 2023-09-13 | Nuisance |
| 2023-09-03 | French bread |
| 2023-05-28 | Bother |
| 2023-03-27 | Big nuisance |
| 2022-06-16 | Hassle |
| 2022-04-20 | Bread: Fr. |
| 2021-12-22 | Bother |
| 2021-12-05 | Something necessary for gain, they say |
| 2021-10-16 | Royal ___ |
| 2020-11-13 | Total inconvenience |
| 2020-09-15 | Pill ... or a reason to take a pill |
| 2020-06-09 | Bother |
| 2020-04-05 | Masochist's pleasure |
| 2019-07-08 | Tylenol target |
| 2018-02-01 | Tough person to tolerate |
| 2017-09-26 | Big nuisance |
| 2017-08-04 | Nuisance |
| 2015-12-29 | Suffering |
| 2014-11-21 | Hassle |
| 2014-08-17 | Pest |
| 2013-12-08 | Distress |
| 2013-07-02 | Ibuprofen target |
| 2013-02-01 | What a dolorimeter measures |
| 2013-01-07 | Ache |
| 2012-05-26 | It may be unbearable |
| 2012-04-23 | Ache |
| 2012-01-06 | Sibling, at times? |
| 2011-06-04 | Nuisance |
| 2011-05-22 | Hassle |
| 2010-11-23 | What lines with stars at the end indicate in comics |
| 2010-03-28 | Pest |
| 2009-10-14 | Analgesic's target |
| 2009-08-24 | Aspirin target |
| 2008-09-10 | Cause of a wince |
| 2008-07-30 | Pest |
| 2008-05-14 | Nuisance |
| 2007-09-23 | Pill |
| 2007-09-06 | Result of punishment |
| 2007-04-24 | Ibuprofen target |
| 2007-03-31 | Baby brother, often |
| 2006-06-11 | Number's target? |
| 2006-01-02 | Feeling that makes you say "Ow!" |
| 2005-05-24 | Cause of a wince |
| 2005-02-06 | Bother |
| 2004-09-07 | What an analgesic stops |
| 2004-06-06 | Arduous chore |
| 2003-11-30 | Neuralgia |
| 1998-07-09 | Annoyance |
| 1998-05-27 | Cause to grimace |
| 1998-04-27 | Hurt |
| 1998-02-09 | Nuisance |
| 1997-08-18 | Excedrin target |
| 1997-07-06 | Annoyance |
| 1995-04-15 | Nice bread |
| 1994-03-31 | Aggrieve |